Mouse Anti-Tarm1 Recombinant Antibody (CBYJT-2004) (CBMAB-T1095-YJ)

Name: Mouse Anti-Tarm1 Recombinant Antibody (CBYJT-2004)
SKU: CBMAB-T1095-YJ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBYJT-2004

Application

WB, IP, IF, ELISA

Immunogen

Specific for an epitope mapping between amino acids 237-259 near the C-terminus of TARM1 of mouse origin

Specificity

Mouse, Rat

Antibody Isotype

IgM

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% gelatin

Preservative

< 0.1% sodium azide

Concentration

0.2 mg/mL

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

T Cell-Interacting, Activating Receptor On Myeloid Cells 1

Introduction

Tarm1 may act as receptor. It negatively regulates TCR-mediated CD4+ T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface. Tarm1 enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils.

Entrez Gene ID

Mouse	245126
Rat	499065

UniProt ID

Mouse	B6A8R8
Rat	D3ZW99

Alternative Names

OLT-2; Gm9904; 9930022N03Rik

Function

May act as receptor (By similarity).
Negatively regulates TCR-mediated CD4+ T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface (PubMed:26311901).
Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity).

Biological Process

Biological Process adaptive immune responseIEA:UniProtKB-KW
Biological Process innate immune responseIEA:UniProtKB-KW
Biological Process negative regulation of CD4-positive, alpha-beta T cell activationIDA:UniProtKB1 Publication

Cellular Location

Cell membrane

Topology

Extracellular: 17-236
Helical: 237-257
Cytoplasmic: 237-257

PTM

N-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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