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Mouse Anti-TAS2R10 Recombinant Antibody (CBYJT-2009) (CBMAB-T1101-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2009
Antibody Isotype
IgG2b, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa1-124 from human TAS2R10 with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-124

Target

Full Name
taste receptor, type 2, member 10
Introduction
TAS2R10 belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
Entrez Gene ID
50839
UniProt ID
Q9NYW0
Alternative Names
Taste 2 Receptor Member 10; Taste Receptor, Type 2, Member 10; T2R10; TRB2; Taste Receptor, Family B, Member 2; Taste Receptor Family B Member 2; Taste Receptor Type 2 Member 10
Function
Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Biological Process
Detection of chemical stimulus involved in sensory perception of bitter taste
Cellular Location
Membrane
Topology
Extracellular: 1-6
Helical: 7-27
Cytoplasmic: 28-42
Helical: 43-63
Extracellular: 64-100
Helical: 101-121
Cytoplasmic: 122-126
Helical: 127-147
Extracellular: 148-179
Helical: 180-200
Cytoplasmic: 201-227
Helical: 228-248
Extracellular: 249-257
Helical: 258-278
Cytoplasmic: 279-307
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For research use only. Not intended for any clinical use.

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