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Mouse Anti-TBCC Recombinant Antibody (CBYJT-2066) (CBMAB-T1163-YJ)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2066
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Full length human recombinant protein of human TBCC(NP_003183) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
tubulin folding cofactor C
Introduction
Cofactor C (TBCC) is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to function in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Entrez Gene ID
UniProt ID
Alternative Names
Tubulin Folding Cofactor C; Tubulin-Specific Chaperone C; CFC; Tubulin-Folding Cofactor C
Function
Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
Biological Process
Biological Process post-chaperonin tubulin folding pathwayIDA:UniProtKB1 Publication
Biological Process protein foldingIBA:GO_Central1 Publication
Biological Process tubulin complex assemblyIBA:GO_Central1 Publication
Cellular Location
Cytoplasm
Detected predominantly in the photoreceptor connecting cilium.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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