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Mouse Anti-TBPL1 Recombinant Antibody (CBYJT-2121) (CBMAB-T1223-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TBPL1 (TATA-Box Binding Protein Like 1). The antibody can be used for immunoassay techniques, such as WB, IP, IF, IHC-P, ELISA.
See all TBPL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat, Mouse
Clone
CBYJT-2121
Antibody Isotype
IgG
Application
WB, IP, IF, IHC-P, ELISA

Basic Information

Immunogen
Amino acids 77-186 mapping at the C-terminus of TLF of human origin
Specificity
Human, Rat, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 77-186

Target

Full Name
TATA-Box Binding Protein Like 1
Introduction
TBPL1 is a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. TBPL1 does not bind to the TATA box and initiates transcription from TATA-less promoters. TBPL1 plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility.
Entrez Gene ID
Human9519
Mouse237336
Rat689030
UniProt ID
HumanP62380
MouseP62340
RatD4A898
Alternative Names
TATA-Box Binding Protein Like 1; TATA Box-Binding Protein-Related Factor 2; Second TBP Of Unique DNA Protein; TBP-Related Factor 2; TBP-Related Protein; TBP-Like Factor; TBP-Like 1; STUD; TRF2; TLP
Function
Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box.
Biological Process
Biological Process acrosome assemblyIEA:Ensembl
Biological Process DNA-templated transcription initiationIBA:GO_Central1 Publication
Biological Process dTTP biosynthetic processIEA:Ensembl
Biological Process spermatid nucleus differentiationIEA:Ensembl
Biological Process transcription by RNA polymerase IITAS:UniProtKB1 Publication
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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