TBPL1

TBPL1 is a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility.

TATA-Box Binding Protein Like 1

Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box.

Biological Process acrosome assemblyIEA:Ensembl
Biological Process DNA-templated transcription initiationIBA:GO_Central1 Publication
Biological Process dTTP biosynthetic processIEA:Ensembl
Biological Process spermatid nucleus differentiationIEA:Ensembl
Biological Process transcription by RNA polymerase IITAS:UniProtKB1 Publication

Cytoplasm
Nucleus