Mouse Anti-TCP11 Recombinant Antibody (CBYJT-2339) (CBMAB-T1454-YJ)

Name: Mouse Anti-TCP11 Recombinant Antibody (CBYJT-2339)
SKU: CBMAB-T1454-YJ
Rating: 5 (1 reviews)

See all TCP11 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYJT-2339

Application

ELISA, WB

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 342-442

More Infomation

Target

Full Name

t-complex 11 homolog (mouse)

Introduction

TCP11 (T-Complex 11) plays a role in the process of sperm capacitation and acrosome reactions. It is a probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway.

Entrez Gene ID

6954

UniProt ID

Q8WWU5

Alternative Names

T-Complex 11; Fertilization-Promoting Peptide Receptor; T-Complex 11 (A Murine Tcp Homolog); T-Complex 11, Testis-Specific; Testis Secretory Sperm-Binding Protein Li 222n; T-Complex Protein 11 Homolog

Function

Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway.

Biological Process

Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathwayISS:UniProtKB
Biological Process germ cell developmentIEP:UniProtKB1 Publication
Biological Process protein kinase A signalingISS:UniProtKB
Biological Process regulation of sperm capacitationISS:UniProtKB
Biological Process signal transductionIBA:GO_Central1 Publication
Biological Process spermatogenesisIEA:UniProtKB-KW

Cellular Location

Membrane
Cell projection, cilium, flagellum
Cytoplasmic vesicle, secretory vesicle, acrosome
Localizes on the acrosomal cap region of acrosome-intact, but not acrosome-reacted sperm. Colocalizes with MROH2B and PRKACA on the acrosome and tail regions in round spermatids and spermatozoa regardless of the capacitation status of the sperm.

Topology

Helical: 330-349

PTM

Constitutively phosphorylated on serine, threonine and tyrosine residues within the head and tail regions of noncapacitated spermatozoa. Phosphorylation on tyrosine residues increases upon sperm capacitation within the acrosomal region in a protein kinase A (PKA)-dependent signaling pathway.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-TCP11 Recombinant Antibody (CBYJT-2339)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-TCP11 Recombinant Antibody (CBYJT-2338) (CAT#: CBMAB-T1453-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry