Sign in or Register   Sign in or Register
  |  

Rabbit Anti-TECPR1 Recombinant Antibody (CBYJT-2494) (CBMAB-T1643-YJ)

Provided herein is a Rabbit monoclonal antibody, which binds to TECPR1 (Tectonin Beta-Propeller Repeat Containing 1). The antibody can be used for immunoassay techniques, such as WB.
See all TECPR1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
CBYJT-2494
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TECPR1 Gene(Protein Coding) Tectonin Beta-Propeller Repeat Containing 1
Introduction
TECPR1 is a tethering factor involved in autophagy. TECPR1 is found at autolysosomes, and is involved in targeting protein aggregates, damaged mitochondria, and bacterial pathogens for autophagy.
Entrez Gene ID
Human25851
Mouse70381
Rat304285
UniProt ID
HumanQ7Z6L1
MouseQ80VP0
RatQ3ZBA0
Alternative Names
Tectonin Beta-Propeller Repeat Containing 1; KIAA1358
Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns3P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
Biological Process
Biological Process autophagosome maturationIMP:UniProtKB1 Publication
Biological Process autophagyIDA:UniProtKB1 Publication
Biological Process macroautophagyIMP:ComplexPortal1 Publication
Biological Process regulation of autophagosome maturationIMP:ComplexPortal1 Publication
Cellular Location
Cytoplasmic vesicle, autophagosome membrane
Lysosome membrane
Localizes to Lysosome membranes, and binds PtdIns3P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-TECPR1 Recombinant Antibody (CBYJT-2494)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare