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Mouse Anti-TFF2 Recombinant Antibody (CBYJT-2682) (CBMAB-T1869-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TFF2 (Trefoil Factor 2). The antibody can be used for immunoassay techniques, such as S-ELISA, ELISA, WB.
See all TFF2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2682
Antibody Isotype
IgG2a, κ
Application
S-ELISA, ELISA, WB

Basic Information

Immunogen
TFF2 (AAH32820, 1 a.a. ~ 129 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-129

Target

Full Name
trefoil factor 2
Introduction
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. TFF2 inhibits gastric acid secretion.
Entrez Gene ID
UniProt ID
Alternative Names
Trefoil Factor 2; Spasmolytic Polypeptide; Spasmolytic Protein 1; Spasmolysin; SML1; SP
Function
Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity).
Biological Process
Biological Process chemokine-mediated signaling pathwaySource:GO_Central1 Publication
Biological Process maintenance of gastrointestinal epitheliumSource:GO_Central1 Publication
Biological Process negative regulation of gastric acid secretionSource:GO_Central1 Publication
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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