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Mouse Anti-TG Recombinant Antibody (CBYJT-2751) (CBMAB-T1954-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TG (Thyroglobulin). The antibody can be used for immunoassay techniques, such as WB, FC, IHC-P, CyTOF.
Host Species
Mouse
Application
WB, FC, IHC-P, CyTOF
Immunogen
Human thyroid follicular cells
Antibody Isotype
IgG
Specificity
Human, Mouse, Rat
Clone
CBYJT-2751
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
Thyroglobulin (TG) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in TG cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in TG are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
Alternative Name
Thyroglobulin; AITD3; TGN; Tg
Entrez Gene ID
UniProt ID
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Cat CBMAB-T1954-YJ
Conjugates
Size
Price $
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Second antibody and isotype control