Mouse Anti-THAP11 Recombinant Antibody (CBCNC-709) (CBMAB-C4319-CN)

Name: Mouse Anti-THAP11 Recombinant Antibody (CBCNC-709)
SKU: CBMAB-C4319-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBCNC-709

Application

ICC, WB

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, trehalose

More Infomation

Target

Full Name

THAP11 Gene(Protein Coding) THAP Domain Containing 11

Introduction

The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008]

Entrez Gene ID

57215

UniProt ID

Q96EK4

Alternative Names

THAP Domain Containing 11; THAP Domain-Containing Protein 11; HRIHFB2206; CTG-B43a; CTG-B45d; RONIN;

Function

Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).

Biological Process

Biological Process cell population proliferationSource:Ensembl
Biological Process electron transport chainSource:Ensembl
Biological Process negative regulation of neuron apoptotic processSource:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IISource:NTNU_SB1 Publication
Biological Process neuron differentiationSource:Ensembl
Biological Process positive regulation of androgen receptor activitySource:Ensembl
Biological Process regulation of mitochondrial transcriptionSource:Ensembl
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication

Cellular Location

Nucleus
Cytoplasm
May be regulated by shuttling of the protein between the cytoplasm and nucleus.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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