Mouse Anti-THEMIS Recombinant Antibody (CBYJT-2965) (CBMAB-T2211-YJ)

Name: Mouse Anti-THEMIS Recombinant Antibody (CBYJT-2965)
SKU: CBMAB-T2211-YJ
Rating: 5 (1 reviews)

See all THEMIS antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYJT-2965

Application

Immunogen

Human THEMIS Recombinant Protein

Specificity

Human, Mouse

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Thymocyte Selection Associated

Introduction

THEMIS is a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. THEMIS functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells.

Entrez Gene ID

Human	387357
Mouse	210757

UniProt ID

Human	Q8N1K5
Mouse	Q8BGW0

Alternative Names

Thymocyte Selection Associated; Thymocyte-Expressed Molecule Involved In Selection; Thymocyte Selection Pathway Associated; C6orf190; C6orf207; Thymocyte Expressed Molecule Involved In Selection; Signaling Phosphoprotein Specific For T Cells; Chromosome 6 Open Reading Frame 207

Function

Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.

Biological Process

Biological Process adaptive immune responseSource:UniProtKB-KW
Biological Process negative T cell selectionSource:UniProtKB
Biological Process positive T cell selectionSource:UniProtKB
Biological Process T cell receptor signaling pathwaySource:UniProtKB

Cellular Location

Cytoplasm
Nucleus

PTM

Phosphorylated on Tyr residues quickly after TCR stimulation.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-THEMIS Recombinant Antibody (CBYJT-2965)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-THEMIS Recombinant Antibody (CBYJT-2964) (CAT#: CBMAB-T2210-YJ)

Rat Anti-Themis Recombinant Antibody (CBYJT-2967) (CAT#: CBMAB-T2214-YJ)

Rat Anti-Themis Recombinant Antibody (12K186) (CAT#: CBMAB-T2212-YJ)

Rabbit Anti-THEMIS Recombinant Antibody (
7G7) (CAT#: V2LY-0725-LY1133)

Mouse Anti-THEMIS Recombinant Antibody (CBYJT-2961) (CAT#: CBMAB-T2207-YJ)

Rat Anti-Themis Recombinant Antibody (CBYJT-2966) (CAT#: CBMAB-T2213-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry