Mouse Anti-THEMIS2 Recombinant Antibody (1C3) (CBMAB-A0953-LY)

Name: Mouse Anti-THEMIS2 Recombinant Antibody (1C3)
SKU: CBMAB-A0953-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1C3

Application

sELISA, ELISA

Immunogen

C1orf38 (AAH31655, 1 a.a. ~ 111 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

THEMIS2 Gene(Protein Coding)

Thymocyte Selection Associated Family Member 2

Entrez Gene ID

9473

UniProt ID

Q5TEJ8

Alternative Names

ICB-1

Function

May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production (PubMed:20644716).
Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (By similarity).

Biological Process

Biological Process cell adhesionSource:ProtInc1 Publication
Biological Process inflammatory responseSource:UniProtKB-KW
Biological Process regulation of B cell activationSource:UniProtKB
Biological Process T cell receptor signaling pathwaySource:GO_Central1 Publication

Cellular Location

Nucleus
Cytoplasm

PTM

Phosphorylation at Tyr-632 is induced by LPS. Phosphorylated by Src kinases (Lck or Fyn) following BCR engagement.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-THEMIS2 Recombinant Antibody (CBLC270-LY) (CAT#: CBMAB-C12496-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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