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Mouse Anti-THRSP Recombinant Antibody (2F8) (CBMAB-A9087-LY)

The product is antibody recognizes THRSP. The antibody 2F8 immunoassay techniques such as: IHC, ELISA.
See all THRSP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2F8
Antibody Isotype
IgG2a, κ
Application
IHC, ELISA

Basic Information

Immunogen
THRSP (NP_003242.1, 1 a.a. ~ 84 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
thyroid hormone responsive (SPOT14 homolog, rat)
Introduction
The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism. [provided by RefSeq]
Entrez Gene ID
7069
UniProt ID
Q92748
Alternative Names
MGC21659; S14; SPOT14
Function
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity).
May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
Biological Process
Biological Process lipid metabolic processSource:ProtInc1 Publication
Biological Process regulation of lipid biosynthetic processSource:UniProtKB
Biological Process regulation of triglyceride biosynthetic processSource:Ensembl
Biological Process response to bacteriumSource:Ensembl
Cellular Location
Nucleus
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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