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Mouse Anti-TIMM13 Recombinant Antibody (CBYJT-3168) (CBMAB-T2442-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TIMM13 (Translocase Of Inner Mitochondrial Membrane 13). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TIMM13 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3168
Antibody Isotype
IgM, κ
Application
ELISA, WB

Basic Information

Immunogen
Full-length recombinant corresponding to aa1-96 from human TIMM13 with GST tag
Specificity
Human
Antibody Isotype
IgM, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
Ascites
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-96

Target

Full Name
Translocase Of Inner Mitochondrial Membrane 13
Introduction
TIMM13 is a member of the evolutionarily conserved TIMM (translocase of inner mitochondrial membrane) family of proteins that play a role as chaperones in the import of proteins from the cytoplasm into the mitochondrial inner membrane. Proteins of this family function in collecting substrate proteins from the translocase of the outer mitochondrial membrane (TOM) complex and delivering them to either the sorting and assembly machinery in the outer mitochondrial membrane (SAM) complex or the TIMM22 complex in the inner mitochondrial membrane. TIMM13 and the translocase of mitochondrial inner membrane 8a protein form a 70 kDa complex in the intermembrane space.
Entrez Gene ID
26517
UniProt ID
Q9Y5L4
Alternative Names
Translocase Of Inner Mitochondrial Membrane 13; TIMM13B; TIMM13A; TIM13B; Translocase Of Inner Mitochondrial Membrane 13 (Yeast) Homolog B; Translocase Of Inner Mitochondrial Membrane 13 Homolog (Yeast)
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
Biological Process
Biological Process protein insertion into mitochondrial inner membraneSource:GO_Central1 Publication
Biological Process protein targeting to mitochondrionSource:ProtInc1 Publication
Biological Process sensory perception of soundSource:ProtInc1 Publication
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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