Mouse Anti-TIMM44 Recombinant Antibody (CF438) (CBMAB-FT089LY)

Name: Mouse Anti-TIMM44 Recombinant Antibody (CF438)
SKU: CBMAB-FT089LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CF438

Application

ELISA, WB, IHC

Immunogen

translocase of inner mitochondrial membrane 44 homolog (yeast)

Specificity

Human, Mouse

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

50% glycerol

Preservative

0.02% sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

TIMM44 Translocase Of Inner Mitochondrial Membrane 44

Introduction

This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma. [provided by RefSeq, Jul 2016]

Entrez Gene ID

Human	10469
Mouse	21856

UniProt ID

Human	O43615
Mouse	O35857

Alternative Names

MIMT44, TIM44

Function

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity).
Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source (By similarity).

Biological Process

Biological Process intracellular protein transportSource:ComplexPortal1 Publication
Biological Process protein import into mitochondrial matrixSource:GO_Central1 Publication
Biological Process protein targeting to mitochondrionSource:ProtInc1 Publication

Cellular Location

Mitochondrion inner membrane
Mitochondrion matrix

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-TIMM44 Recombinant Antibody (CBYJT-3174) (CAT#: CBMAB-T2448-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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