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Mouse Anti-TIMM9 Recombinant Antibody (1D6) (CBMAB-A9106-LY)

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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
1D6
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
TIMM9 (AAH20213, 1 a.a. ~ 89 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
translocase of inner mitochondrial membrane 9 homolog (yeast)
Introduction
TIMM9 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM
Entrez Gene ID
Human26520
Mouse30056
Rat171139
UniProt ID
HumanQ9Y5J7
MouseQ9WV98
RatQ9WV97
Alternative Names
TIM9; TIM9A
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Biological Process
Biological Process protein insertion into mitochondrial inner membraneSource:BHF-UCL1 Publication
Biological Process protein targeting to mitochondrionSource:ProtInc1 Publication
Biological Process sensory perception of soundSource:ProtInc1 Publication
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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