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Mouse Anti-TIMM9 Recombinant Antibody (CBYJT-3186) (CBMAB-T2460-YJ)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYJT-3186
Antibody Isotype
IgG2a, κ
Application
ELISA, IHC, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa1-90 from human TIMM9 (AAH20213) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-90

Target

Introduction
TIMM9 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.
Entrez Gene ID
Human26520
Mouse30056
Rat171139
UniProt ID
HumanQ9Y5J7
MouseQ9WV98
RatQ9WV97
Alternative Names
Translocase Of Inner Mitochondrial Membrane 9; TIM9A; TIM9; Translocase Of Inner Mitochondrial Membrane 9 (Yeast) Homolog; Translocase Of Inner Mitochondrial Membrane 9 Homolog (Yeast); Mitochondrial Import Inner Membrane Translocase Subunit Tim9; Translocase Of Inner Mitochondrial Membrane 9 Homolog; TIMM9A
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Biological Process
Biological Process protein insertion into mitochondrial inner membraneSource:BHF-UCL1 Publication
Biological Process protein targeting to mitochondrionSource:ProtInc1 Publication
Biological Process sensory perception of soundSource:ProtInc1 Publication
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

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