Mouse Anti-TIPIN Recombinant Antibody (CBYJT-3239) (CBMAB-T2522-YJ)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Important for cell survival after DNA damage or replication stress (PubMed:17116885).
May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light (PubMed:17296725).
Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress (PubMed:23359676, PubMed:35585232, PubMed:17102137, PubMed:17116885, PubMed:17296725).
Biological Process cell divisionSource:UniProtKB-KW
Biological Process DNA replication checkpoint signalingSource:HGNC-UCL1 Publication
Biological Process mitotic intra-S DNA damage checkpoint signalingSource:HGNC-UCL1 Publication
Biological Process positive regulation of cell population proliferationSource:HGNC-UCL1 Publication
Biological Process regulation of nuclear cell cycle DNA replicationSource:HGNC-UCL1 Publication
Biological Process replication fork arrestSource:GO_Central1 Publication
Biological Process replication fork protectionSource:GO_Central1 Publication
Biological Process response to UVSource:Ensembl
Nucleus
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
Antibody Pairs
TIPIN Matched Antibody Pair (1208) (CAT#: APMAB-1208LY)
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Mouse Anti-TIPIN Recombinant Antibody (CBYJT-3243) (CAT#: CBMAB-T2526-YJ)
Mouse Anti-TIPIN Recombinant Antibody (CBYJT-3238) (CAT#: CBMAB-T2521-YJ)
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TIPIN Matched Antibody Pair (1208) (CAT#: APMAB-1208LY)
Mouse Anti-TIPIN Recombinant Antibody (CBYJT-3240) (CAT#: CBMAB-T2523-YJ)
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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