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Mouse Anti-TKTL1 Recombinant Antibody (CBYJT-3276) (CBMAB-T2561-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TKTL1 (Transketolase Like 1). The antibody can be used for immunoassay techniques, such as ELISA, IF, WB.
See all TKTL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3276
Antibody Isotype
IgG1, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
Full length recombinant protein corresponding to aa1-596 from TKTL1 with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-596

Target

Full Name
transketolase-like 1
Introduction
TKTL1 is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome.
Entrez Gene ID
8277
UniProt ID
P51854
Alternative Names
Transketolase Like 1; Transketolase-Related Protein; EC 2.2.1.1; TK 2; TKT2; TKR; Transketolase-Like Protein 1; Transketolase-2; Transketolase 2
Function
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
Biological Process
Biological Process glucose catabolic processSource:ProtInc1 Publication
Biological Process thiamine metabolic processSource:ProtInc1 Publication
Cellular Location
Cytoplasm
Nucleus
Predominantly cytoplasmic and to a lesser extent also nuclear (PubMed:16969476).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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