TKTL1

TKTL1 is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome.

Full Name

transketolase-like 1

Function

Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.

Biological Process

Biological Process glucose catabolic processSource:ProtInc1 Publication
Biological Process thiamine metabolic processSource:ProtInc1 Publication

Cellular Location

Cytoplasm
Nucleus
Predominantly cytoplasmic and to a lesser extent also nuclear (PubMed:16969476).

Anti-TKTL1 antibodies

Mouse Anti-TKTL1 Recombinant Antibody (1C10) (CBMAB-A9129-LY)

Datasheet

SDS

Target: TKTL1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1C10

Application*: WB, E

Mouse Anti-TKTL1 Recombinant Antibody (1D6) (CBMAB-A9130-LY)

Datasheet

SDS

Target: TKTL1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1D6

Application*: WB, E

Mouse Anti-TKTL1 Recombinant Antibody (CBYJT-3276) (CBMAB-T2561-YJ)

Datasheet

SDS

Target: TKTL1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJT-3276

Application*: E, IF, WB

Mouse Anti-TKTL1 Recombinant Antibody (CBYJT-3277) (CBMAB-T2562-YJ)

Datasheet

SDS

Target: TKTL1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-3277

Application*: IH, IB

Mouse Anti-TKTL1 Recombinant Antibody (CBYJT-3278) (CBMAB-T2563-YJ)

Datasheet

SDS

Target: TKTL1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3278

Application*: WB, IC, IF

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)