TKTL1
TKTL1 is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome.
Full Name
transketolase-like 1
Function
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
Biological Process
Biological Process glucose catabolic processSource:ProtInc1 Publication
Biological Process thiamine metabolic processSource:ProtInc1 Publication
Biological Process thiamine metabolic processSource:ProtInc1 Publication
Cellular Location
Cytoplasm
Nucleus
Predominantly cytoplasmic and to a lesser extent also nuclear (PubMed:16969476).
Nucleus
Predominantly cytoplasmic and to a lesser extent also nuclear (PubMed:16969476).
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Anti-TKTL1 antibodies
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Target: TKTL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D6
Application*: WB, E
Target: TKTL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C10
Application*: WB, E
Target: TKTL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3278
Application*: WB, IC, IF
Target: TKTL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-3277
Application*: IH, IB
Target: TKTL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-3276
Application*: E, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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