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Mouse Anti-TLN2 Recombinant Antibody (CBYJT-3330) (CBMAB-T2622-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3330
Antibody Isotype
IgG2b
Application
IF, IHC, IP, WB

Basic Information

Immunogen
Talin-2
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Talin 2
Introduction
TLN2 is a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. TLN2 has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton.
Entrez Gene ID
83660
UniProt ID
Q9Y4G6
Alternative Names
ILWEQ
Function
As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity).
Biological Process
Biological Process cell adhesionSource:UniProtKB1 Publication
Biological Process cell-cell adhesionSource:GO_Central1 Publication
Biological Process cell-cell junction assemblySource:UniProtKB1 Publication
Cellular Location
Cytoplasm
Cell junction, focal adhesion
Synapse
Cell membrane
Cytoplasm, cytoskeleton
Focal adhesion plaques and synapses (PubMed:12422219).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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