Mouse Anti-TLN2 Recombinant Antibody (CBYJT-3331) (CBMAB-T2623-YJ)

Name: Mouse Anti-TLN2 Recombinant Antibody (CBYJT-3331)
SKU: CBMAB-T2623-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-3331

Application

IHC, IP, WB

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Talin 2

Introduction

TLN2 is a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. TLN2 has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton.

Entrez Gene ID

83660

UniProt ID

Q9Y4G6

Alternative Names

ILWEQ

Function

As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity).

Biological Process

Biological Process cell adhesionSource:UniProtKB1 Publication
Biological Process cell-cell adhesionSource:GO_Central1 Publication
Biological Process cell-cell junction assemblySource:UniProtKB1 Publication

Cellular Location

Cytoplasm
Cell junction, focal adhesion
Synapse
Cell membrane
Cytoplasm, cytoskeleton
Focal adhesion plaques and synapses (PubMed:12422219).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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