Mouse Anti-TLR10 Recombinant Antibody (CBYY-C0064) (CBMAB-C0245-YY)

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Basic Information

Host Animal
Mouse
Clone
CBYY-C0064
Application
FC
Immunogen
Purified extracellular domain of human TLR10 (amino acids 20-474) (NP_001017388 )
Specificity
Human, Monkey
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
TLR10 Gene(Protein Coding) Toll Like Receptor 10
Entrez Gene ID
Human81793
Monkey697980
UniProt ID
HumanQ9BXR5
MonkeyF7EUU3
Alternative Names
CD164 Molecule; Multi-Glycosylated Core Protein 24; CD164 Antigen, Sialomucin; Endolyn; MGC-24v; MGC-24; MUC-24;
Function
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Biological Process
Biological Process immune responseSource:UniProtKB1 Publication
Biological Process inflammatory responseSource:GO_Central1 Publication
Biological Process innate immune responseSource:ComplexPortal1 Publication
Biological Process MyD88-dependent toll-like receptor signaling pathwaySource:InterPro
Biological Process positive regulation of inflammatory responseSource:InterPro
Biological Process regulation of cytokine productionSource:InterPro
Biological Process toll-like receptor 10 signaling pathwaySource:InterPro
Biological Process toll-like receptor signaling pathwaySource:GO_Central1 Publication
Cellular Location
Membrane
Topology
Extracellular: 20-576
Helical: 577-597
Cytoplasmic: 598-811
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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