Mouse Anti-TM9SF2 Recombinant Antibody (CBYJT-3451) (CBMAB-T2773-YJ)

Name: Mouse Anti-TM9SF2 Recombinant Antibody (CBYJT-3451)
SKU: CBMAB-T2773-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYJT-3451

Application

ELISA

Immunogen

Partial recombinant corresponding to aa116-215 from TM9SF2 (NP_004791) with GST tag. MW of the GST tag alone is 26kD

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 116-215

More Infomation

Target

Full Name

transmembrane 9 superfamily member 2

Introduction

TM9SF2 is a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. TM9SF2 possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. TM9SF2 may function in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome.

Entrez Gene ID

9375

UniProt ID

Q99805

Alternative Names

Transmembrane 9 Superfamily Member 2; P76; Dinucleotide Oxidase Disulfide Thiol Exchanger 3 Superfamily Member 2; Transmembrane Protein 9 Superfamily Member 2; 76 KDa Membrane Protein

Function

In the intracellular compartments, may function as a channel or small molecule transporter.

Biological Process

Biological Process ceramide metabolic processSource:UniProtKB1 Publication
Biological Process glycosphingolipid biosynthetic processSource:UniProtKB1 Publication
Biological Process protein localization to membraneSource:GO_Central1 Publication
Biological Process regulation of heparan sulfate proteoglycan biosynthetic processSource:UniProtKB1 Publication

Cellular Location

Endosome membrane
Golgi outpost
Cytoplasm, cytoskeleton, microtubule organizing center
Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation.

Topology

Lumenal: 29-300
Helical: 301-321
Cytoplasmic: 322-374
Helical: 375-395
Lumenal: 396-398
Helical: 399-419
Cytoplasmic: 420-437
Helical: 438-458
Lumenal: 459-466
Helical: 467-487
Cytoplasmic: 488-522
Helical: 523-543
Lumenal: 544-554
Helical: 555-575
Cytoplasmic: 576-591
Helical: 592-612
Lumenal: 613-631
Helical: 632-652
Cytoplasmic: 653-663

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-TM9SF2 Recombinant Antibody (1C2) (CAT#: CBMAB-A9209-LY)

Isotype control

For research use only. Not intended for any clinical use.

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