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Mouse Anti-TM9SF2 Recombinant Antibody (CBYJT-3451) (CBMAB-T2773-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TM9SF2 (Transmembrane 9 Superfamily Member 2). The antibody can be used for immunoassay techniques, such as ELISA.
See all TM9SF2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3451
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa116-215 from TM9SF2 (NP_004791) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 116-215

Target

Full Name
transmembrane 9 superfamily member 2
Introduction
TM9SF2 is a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. TM9SF2 possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. TM9SF2 may function in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome.
Entrez Gene ID
9375
UniProt ID
Q99805
Alternative Names
Transmembrane 9 Superfamily Member 2; P76; Dinucleotide Oxidase Disulfide Thiol Exchanger 3 Superfamily Member 2; Transmembrane Protein 9 Superfamily Member 2; 76 KDa Membrane Protein
Function
In the intracellular compartments, may function as a channel or small molecule transporter.
Biological Process
Biological Process ceramide metabolic processSource:UniProtKB1 Publication
Biological Process glycosphingolipid biosynthetic processSource:UniProtKB1 Publication
Biological Process protein localization to membraneSource:GO_Central1 Publication
Biological Process regulation of heparan sulfate proteoglycan biosynthetic processSource:UniProtKB1 Publication
Cellular Location
Endosome membrane
Golgi outpost
Cytoplasm, cytoskeleton, microtubule organizing center
Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation.
Topology
Lumenal: 29-300
Helical: 301-321
Cytoplasmic: 322-374
Helical: 375-395
Lumenal: 396-398
Helical: 399-419
Cytoplasmic: 420-437
Helical: 438-458
Lumenal: 459-466
Helical: 467-487
Cytoplasmic: 488-522
Helical: 523-543
Lumenal: 544-554
Helical: 555-575
Cytoplasmic: 576-591
Helical: 592-612
Lumenal: 613-631
Helical: 632-652
Cytoplasmic: 653-663
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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