TM9SF2

TM9SF2 is a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. TM9SF2 possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. TM9SF2 may function in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome.

Full Name

transmembrane 9 superfamily member 2

Function

In the intracellular compartments, may function as a channel or small molecule transporter.

Biological Process

Biological Process ceramide metabolic processSource:UniProtKB1 Publication
Biological Process glycosphingolipid biosynthetic processSource:UniProtKB1 Publication
Biological Process protein localization to membraneSource:GO_Central1 Publication
Biological Process regulation of heparan sulfate proteoglycan biosynthetic processSource:UniProtKB1 Publication

Cellular Location

Endosome membrane
Golgi outpost
Cytoplasm, cytoskeleton, microtubule organizing center
Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation.

Topology

Lumenal: 29-300
Helical: 301-321
Cytoplasmic: 322-374
Helical: 375-395
Lumenal: 396-398
Helical: 399-419
Cytoplasmic: 420-437
Helical: 438-458
Lumenal: 459-466
Helical: 467-487
Cytoplasmic: 488-522
Helical: 523-543
Lumenal: 544-554
Helical: 555-575
Cytoplasmic: 576-591
Helical: 592-612
Lumenal: 613-631
Helical: 632-652
Cytoplasmic: 653-663

Anti-TM9SF2 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-TM9SF2 Recombinant Antibody (1C2) (CBMAB-A9209-LY)

Datasheet

SDS

Target: TM9SF2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1C2

Application*: SE, E

Mouse Anti-TM9SF2 Recombinant Antibody (CBYJT-3451) (CBMAB-T2773-YJ)

Datasheet

SDS

Target: TM9SF2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-3451

Application*: E

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)