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Mouse Anti-TRAPPC10 Recombinant Antibody (5B4) (CBMAB-A9213-LY)

The product is antibody recognizes TMEM1. The antibody 5B4 immunoassay techniques such as: WB, ELISA.
See all TRAPPC10 antibodies
Published Data

Summary

Host Animal
Mouse
Specificity
Human
Clone
5B4
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
TMEM1 (NP_003265, 1162 a.a. ~ 1257 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Trafficking Protein Particle Complex 10
Introduction
The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1. [provided by RefSeq]
Entrez Gene ID
UniProt ID
Alternative Names
EHOC-1; EHOC1; FLJ54223; FLJ54817; FLJ55683; GT334; MGC126777; TMEM1; TRS130; TRS30
Function
Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether.
Biological Process
Biological Process early endosome to Golgi transport Source:GO_Central1 Publication
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport Source:ComplexPortal1 Publication
Biological Process intra-Golgi vesicle-mediated transport Source:GO_Central1 Publication
Biological Process vesicle coating Source:ComplexPortal1 Publication
Biological Process vesicle tethering Source:ComplexPortal1 Publication
Cellular Location
Golgi apparatus, cis-Golgi network
Involvement in disease
Defects in this gene may cause an autosomal recessive disorder characterized by severe intellectual disability, poor speech and aggressive behavior.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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