Mouse Anti-TMOD2 Recombinant Antibody (CBYJT-3546) (CBMAB-T2872-YJ)

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Basic Information

Host Animal
Mouse
Clone
CBYJT-3546
Application
WB
Immunogen
Synthetic peptide
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
TMOD2 Gene(Protein Coding) Tropomodulin 2
Introduction
TMOD2 is a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. TMOD2 caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin.
Entrez Gene ID
UniProt ID
Alternative Names
Tropomodulin 2; Neuronal Tropomodulin; N-TMOD; NTMOD; Tropomodulin 2 (Neuronal); Tropomodulin-2
Function
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).
Biological Process
Biological Process actin filament organizationSource:GO_Central1 Publication
Biological Process learning or memorySource:Ensembl
Biological Process muscle contractionSource:GO_Central1 Publication
Biological Process myofibril assemblySource:GO_Central1 Publication
Biological Process nervous system developmentSource:ProtInc1 Publication
Biological Process neuron-neuron synaptic transmissionSource:Ensembl
Biological Process pointed-end actin filament cappingSource:InterPro
Biological Process positive regulation of G protein-coupled receptor signaling pathwaySource:Ensembl
Cellular Location
Cytoplasm, cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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