Mouse Anti-TMPO Recombinant Antibody (3A3) (CBMAB-L2678-YJ)

Name: Mouse Anti-TMPO Recombinant Antibody (3A3)
SKU: CBMAB-L2678-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

3A3

Application

WB, IP, ICC, IF

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 650-750 of Human LAP2 alpha.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 650 - 750

More Infomation

Target

Full Name

Thymopoietin

Introduction

TMPO resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. TMPO may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Entrez Gene ID

7112

UniProt ID

P42166

Alternative Names

Thymopoietin; Thymopoietin-Related Peptide Isoforms Beta/Gamma; Thymopoietin-Related Peptide Isoform Alpha; LEM Domain Containing 4; TP Beta/Gamma; TP Alpha; LAP2; Thymopoietin, Isoforms Beta/Gamma; Lamina-Associated Polypeptide 2

Function

May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.
TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide.

Cellular Location

Nucleus
Chromosome
Expressed diffusely throughout the nucleus.

PTM

Phosphorylated in a mitose-specific manner.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-TMPO Recombinant Antibody (3A3) (CAT#: CBMAB-CP1348-LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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