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Mouse Anti-TMX3 Recombinant Antibody (CBYJT-3591) (CBMAB-T2919-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TMX3 (Thioredoxin Related Transmembrane Protein 3). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all TMX3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3591
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Thioredoxin Related Transmembrane Protein 3
Introduction
TMX3 is a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by TMX3 has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. TMX3 is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of TMX3 in humans and zebrafish is associated with microphthalmia.
Entrez Gene ID
54495
UniProt ID
Q96JJ7
Alternative Names
Thioredoxin Related Transmembrane Protein 3; Protein Disulfide Isomerase Family A, Member 13; Thioredoxin-Related Transmembrane Protein 3; Thioredoxin Domain-Containing Protein 10; Thioredoxin Domain Containing 10; EC 5.3.4.1
Function
Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase.
Biological Process
Peptidyl-cysteine oxidation
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 25-375
Helical: 376-396
Cytoplasmic: 397-454
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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