Rat Anti-Tnfrsf22 Recombinant Antibody (Lucy1) (CBMAB-D2325-YC)

Name: Rat Anti-Tnfrsf22 Recombinant Antibody (Lucy1)
SKU: CBMAB-D2325-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Rat

Clone

Lucy1

Application

Immunogen

Fusion protein, corresponding to amino acids 1-170 (the extracellular domain) of Mouse DcTRAILR2, the long splice variant of mouse DcTRAIL-R2, fused to the Fc portion of human IgG1

Specificity

Mouse

Antibody Isotype

IgG2a

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Tumor Necrosis Factor Receptor Superfamily, Member 22

Introduction

Tnfrsf22 has ubiquitous expression in limb E14.5 (RPKM 3.9), subcutaneous fat pad adult (RPKM 2.4) and 25 other tissues.

Entrez Gene ID

79202

UniProt ID

Q9ER62

Alternative Names

SOBa; Tnfrh2; Tnfrsf1al2; mDcTrailr2; 2810028K06Rik; C130035G06Rik

Function

Receptor for the cytotoxic ligand TNFSF10/TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis possibly through ligand competition. Cannot induce the NF-kappa-B pathway.

Biological Process

Biological Process negative regulation of extrinsic apoptotic signaling pathway via death domain receptors Source:MGI1 Publication
Biological Process positive regulation of apoptotic process Source:GO_Central1 Publication
Biological Process TRAIL-activated apoptotic signaling pathway Source:GO_Central1 Publication

Cellular Location

Isoform 1
Cell membrane
Isoform 2
Secreted

Topology

Cytoplasmic: 42-349
Helical: 350-370
Extracellular: 371-655

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Rat Anti-Tnfrsf22 Recombinant Antibody (6D350) (CAT#: CBMAB-D2324-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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