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Rat Anti-Tnfrsf23 Recombinant Antibody (CBYJT-3842) (CBMAB-T3236-YJ)

Provided herein is a Rat monoclonal antibody, which binds to Tnfrsf23 (Tumor Necrosis Factor Receptor Superfamily, Member 23). The antibody can be used for immunoassay techniques, such as ICC, WB.
See all Tnfrsf23 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYJT-3842
Antibody Isotype
IgG
Application
ICC, WB

Basic Information

Immunogen
Recombinant protein corresponding to mouse TNFRSF23
Specificity
Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Tumor Necrosis Factor Receptor Superfamily, Member 23
Introduction
Tnfrsf23 is a member of the tumor necrosis factor superfamily of proteins. Tnfrsf23 has been shown to bind to the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), but to have no signaling capacity. Tnfrsf23 shows elevated expression in mice with diet-induced fatty liver disease. Tnfrsf23 and other family members are present in a gene cluster on chromosome 7.
Entrez Gene ID
79201
UniProt ID
Q9ER63
Alternative Names
SOB; mSOB; Tnfrh1; TNFRSFH23; Tnfrsf1al1; mDcTRAILR1
Function
Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis through ligand competition. Cannot induce the NF-kappa-B pathway.
Biological Process
Biological Process activation-induced cell death of T cells Source:GO_Central1 Publication
Biological Process extrinsic apoptotic signaling pathway in absence of ligand Source:GO_Central1 Publication
Biological Process motor neuron apoptotic process Source:GO_Central1 Publication
Biological Process necroptotic signaling pathway Source:GO_Central1 Publication
Biological Process negative regulation of apoptotic process Source:GO_Central1 Publication
Biological Process negative regulation of extrinsic apoptotic signaling pathway via death domain receptors Source:MGI1 Publication
Biological Process positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Source:GO_Central1 Publication
Biological Process regulation of stress-activated MAPK cascade Source:GO_Central1 Publication
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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