Rat Anti-Tnfrsf23 Recombinant Antibody (CBYJT-3842) (CBMAB-T3236-YJ)

Name: Rat Anti-Tnfrsf23 Recombinant Antibody (CBYJT-3842)
SKU: CBMAB-T3236-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

CBYJT-3842

Application

ICC, WB

Immunogen

Recombinant protein corresponding to mouse TNFRSF23

Specificity

Mouse

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Tumor Necrosis Factor Receptor Superfamily, Member 23

Introduction

Tnfrsf23 is a member of the tumor necrosis factor superfamily of proteins. Tnfrsf23 has been shown to bind to the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), but to have no signaling capacity. Tnfrsf23 shows elevated expression in mice with diet-induced fatty liver disease. Tnfrsf23 and other family members are present in a gene cluster on chromosome 7.

Entrez Gene ID

79201

UniProt ID

Q9ER63

Alternative Names

SOB; mSOB; Tnfrh1; TNFRSFH23; Tnfrsf1al1; mDcTRAILR1

Function

Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis through ligand competition. Cannot induce the NF-kappa-B pathway.

Biological Process

Biological Process activation-induced cell death of T cells Source:GO_Central1 Publication
Biological Process extrinsic apoptotic signaling pathway in absence of ligand Source:GO_Central1 Publication
Biological Process motor neuron apoptotic process Source:GO_Central1 Publication
Biological Process necroptotic signaling pathway Source:GO_Central1 Publication
Biological Process negative regulation of apoptotic process Source:GO_Central1 Publication
Biological Process negative regulation of extrinsic apoptotic signaling pathway via death domain receptors Source:MGI1 Publication
Biological Process positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Source:GO_Central1 Publication
Biological Process regulation of stress-activated MAPK cascade Source:GO_Central1 Publication

Cellular Location

Cell membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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