Sign in or Register   Sign in or Register
  |  

Rabbit Anti-TNFRSF9 Recombinant Antibody (CBR051F) (CBMAB-BT091LY)

The product is antibody recognizes TNFRSF9. The antibody CBR051F immunoassay techniques such as: WB, IP, IHC, ICC.
See all TNFRSF9 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBR051F
Antibody Isotype
IgG
Application
WB, IP, IHC, ICC

Basic Information

Immunogen
aa 24-189 (ECD)
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TNFRSF9 Gene(Protein Coding) TNF Receptor Superfamily Member 9
Introduction
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008]
Entrez Gene ID
3604
UniProt ID
Q07011
Alternative Names
TNF Superfamily Member 9; Tumor Necrosis Factor (Ligand) Superfamily, Member 9; Homolog Of Mouse 4-1BB-L; Receptor 4-1BB Ligand; 4-1BB Ligand; 4-1BBL; Tumor Necrosis Factor Ligand Superfamily Member 9;
Function
Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Biological Process
Biological Process apoptotic process Source:ProtInc1 Publication
Biological Process negative regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process regulation of cell population proliferation Source:GO_Central1 Publication
Biological Process regulation of immature T cell proliferation in thymus Source:Ensembl
Cellular Location
Membrane
Topology
Extracellular: 24-186
Helical: 187-213
Cytoplasmic: 214-255
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-TNFRSF9 Recombinant Antibody (CBR051F)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare