Mouse Anti-TNFSF13 Recombinant Antibody (CBYJT-3927) (CBMAB-T3334-YJ)

Name: Mouse Anti-TNFSF13 Recombinant Antibody (CBYJT-3927)
SKU: CBMAB-T3334-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYJT-3927

Application

Immunogen

Recombinant protein corresponding to human TNFSF13

Specificity

Human

Antibody Isotype

IgG2

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

tumor necrosis factor (ligand) superfamily, member 13

Introduction

TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. It is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. TNFSF13 and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM.

Entrez Gene ID

8741

UniProt ID

O75888

Alternative Names

TNF Superfamily Member 13; Tumor Necrosis Factor (Ligand) Superfamily, Member 13; TNF- And APOL-Related Leukocyte Expressed Ligand 2; A Proliferation-Inducing Ligand; TALL-2; TRDL-1; APRIL; TALL2; ZTNF2; Tumor Necrosis Factor Ligand Superfamily Member 13

Function

Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.

Biological Process

Biological Process immune response Source:InterPro
Biological Process positive regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process positive regulation of isotype switching to IgA isotypes Source:MGI1 Publication
Biological Process signal transduction Source:ProtInc1 Publication

Cellular Location

Secreted

PTM

The precursor is cleaved by furin.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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