WB, IHC-P, IF/ICC, FC
A full length human recombinant protein was used as the immunogen for this TL1A antibody
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
TNF Superfamily Member 15; Vascular Endothelial Cell Growth Inhibitor; TNF Ligand-Related Molecule 1; Tumor Necrosis Factor (Ligand) Superfamily, Member 15; Vascular Endothelial Growth Inhibitor-192A; TNF Superfamily Ligand TL1A; VEGI; TL1;