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Mouse Anti-Tnk1 Recombinant Antibody (170CT7.5.4) (CBMAB-T3447-YJ)


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Summary

Host Animal
Mouse
Specificity
Mouse
Clone
170CT7.5.4
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Preservative
0.1% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TNK1 Tyrosine Kinase Non Receptor 1
Introduction
Tnk1 may function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. It Could specifically be involved in phospholipid signal transduction (By similarity). It is involved in negative regulation of cell growth. Tnk1 has tumor suppressor properties. It plays a negative regulatory role in the Ras-MAPK pathway.
Entrez Gene ID
83813
UniProt ID
Q99ML2
Alternative Names
Kos1; Tnk1a; Tnk1b
Function
Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
Biological Process
Cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Protein autophosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Protein phosphorylationManual Assertion Based On ExperimentTAS:ProtInc
Transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Membrane
PTM
Autophosphorylated on tyrosine residues.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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