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Mouse Anti-TNNI3K Recombinant Antibody (CBYJT-4090) (CBMAB-T3525-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TNNI3K (TNNI3 Interacting Kinase). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all TNNI3K antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4090
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TNNI3 Interacting Kinase
Introduction
TNNI3K is a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. TNNI3K contains ankyrin repeat, protein kinase and serine-rich domains and is thought to function in cardiac physiology.
Entrez Gene ID
51086
UniProt ID
Q59H18
Alternative Names
TNNI3 Interacting Kinase; Cardiac Troponin I-Interacting Kinase; Cardiac Ankyrin Repeat Kinase; CARK; Serine/Threonine-Protein Kinase TNNI3K; TNNI3-Interacting Kinase; EC 2.7.11.1; CCDD
Function
May play a role in cardiac physiology.
Biological Process
Biological Process bundle of His cell to Purkinje myocyte communication Source:BHF-UCL1 Publication
Biological Process protein phosphorylation Source:UniProtKB1 Publication
Biological Process regulation of cardiac conduction Source:BHF-UCL1 Publication
Biological Process regulation of cardiac muscle contraction Source:BHF-UCL1 Publication
Biological Process regulation of heart rate Source:BHF-UCL1 Publication
Biological Process regulation of postsynapse organization Source:GO_Central1 Publication
Cellular Location
Nucleus
Cytoplasm
Expressed at lower levels in the cytoplasm.
Involvement in disease
Cardiac conduction disease with or without dilated cardiomyopathy (CCDD):
A cardiac disorder characterized by atrial tachyarrhythmia and conduction system disease. Some patients have dilated cardiomyopathy.
PTM
Autophosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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