Mouse Anti-TNNI3K Recombinant Antibody (CBYJT-4090) (CBMAB-T3525-YJ)

Name: Mouse Anti-TNNI3K Recombinant Antibody (CBYJT-4090)
SKU: CBMAB-T3525-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-4090

Application

WB, IP, IF, ELISA

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TNNI3 Interacting Kinase

Introduction

TNNI3K is a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. TNNI3K contains ankyrin repeat, protein kinase and serine-rich domains and is thought to function in cardiac physiology.

Entrez Gene ID

51086

UniProt ID

Q59H18

Alternative Names

TNNI3 Interacting Kinase; Cardiac Troponin I-Interacting Kinase; Cardiac Ankyrin Repeat Kinase; CARK; Serine/Threonine-Protein Kinase TNNI3K; TNNI3-Interacting Kinase; EC 2.7.11.1; CCDD

Function

May play a role in cardiac physiology.

Biological Process

Biological Process bundle of His cell to Purkinje myocyte communication Source:BHF-UCL1 Publication
Biological Process protein phosphorylation Source:UniProtKB1 Publication
Biological Process regulation of cardiac conduction Source:BHF-UCL1 Publication
Biological Process regulation of cardiac muscle contraction Source:BHF-UCL1 Publication
Biological Process regulation of heart rate Source:BHF-UCL1 Publication
Biological Process regulation of postsynapse organization Source:GO_Central1 Publication

Cellular Location

Nucleus
Cytoplasm
Expressed at lower levels in the cytoplasm.

Involvement in disease

Cardiac conduction disease with or without dilated cardiomyopathy (CCDD):
A cardiac disorder characterized by atrial tachyarrhythmia and conduction system disease. Some patients have dilated cardiomyopathy.

PTM

Autophosphorylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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