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TNNI3K

TNNI3K is a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. TNNI3K contains ankyrin repeat, protein kinase and serine-rich domains and is thought to function in cardiac physiology.

Full Name

TNNI3 Interacting Kinase

Function

May play a role in cardiac physiology.

Biological Process

Biological Process bundle of His cell to Purkinje myocyte communication Source:BHF-UCL1 Publication
Biological Process protein phosphorylation Source:UniProtKB1 Publication
Biological Process regulation of cardiac conduction Source:BHF-UCL1 Publication
Biological Process regulation of cardiac muscle contraction Source:BHF-UCL1 Publication
Biological Process regulation of heart rate Source:BHF-UCL1 Publication
Biological Process regulation of postsynapse organization Source:GO_Central1 Publication

Cellular Location

Nucleus
Cytoplasm
Expressed at lower levels in the cytoplasm.

Involvement in disease

Cardiac conduction disease with or without dilated cardiomyopathy (CCDD):
A cardiac disorder characterized by atrial tachyarrhythmia and conduction system disease. Some patients have dilated cardiomyopathy.

PTM

Autophosphorylated.

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Anti-TNNI3K antibodies

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Mouse Anti-TNNI3K Recombinant Antibody (CBYJT-4090) (CBMAB-T3525-YJ)

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Target: TNNI3K

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-4090

Application*: WB, IP, IF, E

Human Recombinant TNNI3K, Active protein, GST Tag (V2LY-0526-LY7314)

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Target: TNNI3K

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: 300-end

Tag: GST Tag

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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