Sign in or Register   Sign in or Register
  |  

Mouse Anti-TNNT1 Recombinant Antibody (CBXS-5643) (CBMAB-S0520-CQ)

This product is a mouse antibody that recognizes TNNT1. The antibody CBXS-5643 can be used for immunoassay techniques such as: WB.
See all TNNT1 antibodies

Summary

Host Animal
Mouse
Specificity
Chicken, Rat, Mouse, Human
Clone
CBXS-5643
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Purified rabbit skeletal muscle troponin I
Specificity
Chicken, Rat, Mouse, Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Troponin T1, Slow Skeletal Type
Entrez Gene ID
Human7138
Mouse21955
Rat171409
Chicken396009
UniProt ID
HumanP13805
MouseO88346
RatQ7TNB2
ChickenA0A1D5NYZ1
Alternative Names
ANM; NEM5; STNT; TNT; TNTS
Function
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Biological Process
Biological Process muscle contraction Source:GO_Central1 Publication
Biological Process negative regulation of muscle contraction Source:UniProtKB1 Publication
Biological Process sarcomere organization Source:GO_Central1 Publication
Biological Process skeletal muscle contraction Source:UniProtKB1 Publication
Biological Process slow-twitch skeletal muscle fiber contraction Source:GO_Central1 Publication
Biological Process transition between fast and slow fiber Source:Ensembl
Cellular Location
cytosol
troponin complex
Involvement in disease
Nemaline myopathy 5 (NEM5):
A form of nemaline myopathy. Nemaline myopathies are muscular disorders characterized by muscle weakness of varying severity and onset, and abnormal thread-like or rod-shaped structures in muscle fibers on histologic examination. Nemaline myopathy type 5 is a severe and progressive form common among Old Order Amish. Affected infants display tremors with hypotonia and mild contractures of the shoulders and hips. Proximal contractures progressively weaken and a pectus carinatum deformity develops before children die of respiratory insufficiency, usually in the second year.
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Anti-TNNT1 Recombinant Antibody (CBXS-5643)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare