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Mouse Anti-TNS4 Recombinant Antibody (12K185) (CBMAB-T3571-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TNS4 (Tensin 4). The antibody can be used for immunoassay techniques, such as IHC, WB.
See all TNS4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
12K185
Antibody Isotype
IgG1
Application
IHC, WB

Basic Information

Immunogen
Recombinant corresponding to aa2-107 from human Tensin 4 expressed in E. coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 2-107

Target

Full Name
TNS4
Introduction
TNS4 (Tensin 4) is a Protein Coding gene. Diseases related to TNS4 include Colorectal Cancer. Among its related pathways are MET promotes cell motility and Signaling by GPCR. Gene Ontology (GO) annotations related to TNS4 include actin binding. An important paralog of TNS4 is TNS1.
Entrez Gene ID
84951
UniProt ID
Q8IZW8
Alternative Names
Tensin 4; C-Terminal Tensin-Like Protein; C Terminal Tensin Like; CTEN; Tensin-4; PP14434
Function
May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity).
May promote apoptosis, via its cleavage by caspase-3.
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process protein localization Source:UniProtKB1 Publication
Cellular Location
Cell junction, focal adhesion
Cytoplasm, cytoskeleton
PTM
Proteolytically cleaved by caspase-3 during apoptosis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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