Mouse Anti-TNS4 Antibody (13E8) (CBMAB-1678CQ)

Name: Mouse Anti-TNS4 Antibody (13E8)
SKU: CBMAB-1678CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

13E8

Application

ELISA, MA

Immunogen

Recombinant protein (aa 436-574; SH2 domain)

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TNS4

Introduction

TNS4 (Tensin 4) may be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. It can promote apoptosis, via its cleavage by caspase-3. Diseases associated with TNS4 include Colorectal Cancer. Among its related pathways are MET promotes cell motility and Signaling by GPCR. GO annotations related to this gene include actin binding.

Entrez Gene ID

84951

UniProt ID

Q8IZW8

Alternative Names

CTEN; PP14434

Function

May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity).
May promote apoptosis, via its cleavage by caspase-3.

Biological Process

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process protein localization Source:UniProtKB1 Publication

Cellular Location

Cell junction, focal adhesion
Cytoplasm, cytoskeleton

PTM

Proteolytically cleaved by caspase-3 during apoptosis.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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