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Mouse Anti-TOM1L1 Recombinant Antibody (CBYJT-4162) (CBMAB-T3615-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4162
Antibody Isotype
IgG1
Application
WB, IHC-P, IHC-Fr

Basic Information

Immunogen
GST-Tom1L1 fusion protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Target Of Myb1 Like 1 Membrane Trafficking Protein
Introduction
TOM1L1 (Target Of Myb1 Like 1 Membrane Trafficking Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to TOM1L1 include protein kinase binding and ubiquitin binding. An important paralog of TOM1L1 is TOM1L2.
Entrez Gene ID
10040
UniProt ID
O75674
Alternative Names
Target Of Myb1 Like 1 Membrane Trafficking Protein; Src-Activating And Signaling Molecule Protein; Target Of Myb-Like Protein 1; SRCASM; Target Of Myb1 (Chicken) Homolog-Like 1; Target Of Myb1 (Chicken)-Like 1; TOM1-Like Protein 1
Function
Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).
Biological Process
Biological Process activation of protein kinase activity Source:UniProtKB1 Publication
Biological Process negative regulation of mitotic nuclear division Source:UniProtKB1 Publication
Biological Process positive regulation of protein autophosphorylation Source:UniProtKB1 Publication
Biological Process protein transport Source:UniProtKB-KW
Biological Process signal transduction Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Source:HGNC-UCL1 Publication
Cellular Location
Golgi apparatus, Golgi stack
Endosome membrane
Cytoplasm
Membrane
A small proportion is membrane-associated.
PTM
Phosphorylated on tyrosines by FYN and LYN.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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