TOM1L1
TOM1L1 (Target Of Myb1 Like 1 Membrane Trafficking Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to TOM1L1 include protein kinase binding and ubiquitin binding. An important paralog of TOM1L1 is TOM1L2.
Full Name
Target Of Myb1 Like 1 Membrane Trafficking Protein
Function
Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).
Biological Process
Biological Process activation of protein kinase activity Source:UniProtKB1 Publication
Biological Process negative regulation of mitotic nuclear division Source:UniProtKB1 Publication
Biological Process positive regulation of protein autophosphorylation Source:UniProtKB1 Publication
Biological Process protein transport Source:UniProtKB-KW
Biological Process signal transduction Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Source:HGNC-UCL1 Publication
Biological Process negative regulation of mitotic nuclear division Source:UniProtKB1 Publication
Biological Process positive regulation of protein autophosphorylation Source:UniProtKB1 Publication
Biological Process protein transport Source:UniProtKB-KW
Biological Process signal transduction Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Source:HGNC-UCL1 Publication
Cellular Location
Golgi apparatus, Golgi stack
Endosome membrane
Cytoplasm
Membrane
A small proportion is membrane-associated.
Endosome membrane
Cytoplasm
Membrane
A small proportion is membrane-associated.
PTM
Phosphorylated on tyrosines by FYN and LYN.
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Anti-TOM1L1 antibodies
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Target: TOM1L1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4164
Application*: WB
Target: TOM1L1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4163
Application*: WB, IF, IC
Target: TOM1L1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4162
Application*: WB, P, C
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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