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Rabbit Anti-TPGS1 Recombinant Antibody (CBYJT-4320) (CBMAB-T3801-YJ)

Provided herein is a Rabbit monoclonal antibody, which binds to TPGS1 (Tubulin Polyglutamylase Complex Subunit 1). The antibody can be used for immunoassay techniques, such as WB, IP, FC.
See all TPGS1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Rat, Mouse
Clone
CBYJT-4320
Antibody Isotype
IgG
Application
WB, IP, FC

Basic Information

Immunogen
Recombinant fragment within Human TPGS1 aa 1-150. The exact sequence is proprietary.
Specificity
Human, Rat, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-150

Target

Full Name
Tubulin Polyglutamylase Complex Subunit 1
Introduction
TPGS1 (Tubulin Polyglutamylase Complex Subunit 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to TPGS1 include microtubule binding and tubulin-glutamic acid ligase activity.
Entrez Gene ID
Human91978
Mouse110012
Rat691093
UniProt ID
HumanQ6ZTW0
MouseQ99MS8
RatD4A463
Alternative Names
Tubulin Polyglutamylase Complex Subunit 1; C19orf20; PGs1; Chromosome 19 Open Reading Frame 20; Gene Trap ROSA B-Geo 22; GTRGEO22
Function
Subunit of the tubulin polyglutamylase complex (TPGC). The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility (Probable). May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity).
Biological Process
Biological Process adult behavior Source:Ensembl
Biological Process chemical synaptic transmission Source:Ensembl
Biological Process protein polyglutamylation Source:GO_Central1 Publication
Biological Process sperm axoneme assembly Source:Ensembl
Biological Process vesicle localization Source:Ensembl
Cellular Location
Cytoplasm, cytoskeleton, cilium axoneme
Cytoplasm, cytoskeleton, flagellum axoneme
Cytoplasm, cytoskeleton, cilium basal body
Cytoplasm, cytoskeleton, flagellum basal body
Cell projection, axon
Cell projection, dendrite
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite
Associated with microtubules from neurites, centrosomes, basal bodies and axonemes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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