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Mouse Anti-TPTE2 Recombinant Antibody (978CT6.1.4) (CBMAB-T3938-YJ)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
978CT6.1.4
Antibody Isotype
IgG2a
Application
WB, ELISA

Basic Information

Immunogen
Purified His-tagged TPIPb protein was used to produced this monoclonal antibody
Specificity
Human, Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
Ascites
Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2
Introduction
TPTE2 is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids.
Entrez Gene ID
93492
UniProt ID
Q6XPS3
Alternative Names
Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2; TPTE And PTEN Homologous Inositol Lipid Phosphatase; Lipid Phosphatase TPIP; TPIP; Transmembrane Phosphoinositide 3-Phosphatase And Tensin 2-Like Protein; Phosphatidylinositol 3, 4, 5-Trisphosphate 3-Phosphatase TPTE2; PTEN-Like Inositol Lipid Phosphatase; TPIP Lipid Phosphatase; EC 3.1.3.67
Function
Acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate.
Isoform 4
Shows no phosphoinositide phosphatase activity.
Biological Process
Biological Process cell motility Source:GO_Central1 Publication
Biological Process dephosphorylation Source:GO_Central1 Publication
Biological Process negative regulation of cell population proliferation Source:GO_Central1 Publication
Biological Process phosphatidylinositol 3-kinase signaling Source:GO_Central1 Publication
Biological Process phosphatidylinositol biosynthetic process Source:Reactome
Biological Process phosphatidylinositol dephosphorylation Source:GO_Central1 Publication
Biological Process protein dephosphorylation Source:GO_Central1 Publication
Biological Process regulation of protein kinase B signaling Source:GO_Central1 Publication
Cellular Location
Isoform 3
Endoplasmic reticulum membrane
Isoform 1
Endoplasmic reticulum membrane
Golgi apparatus membrane
Isoform 4
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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