Mouse Anti-TPTE2 Recombinant Antibody (978CT6.1.4) (CBMAB-T3938-YJ)

Name: Mouse Anti-TPTE2 Recombinant Antibody (978CT6.1.4)
SKU: CBMAB-T3938-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

978CT6.1.4

Application

WB, ELISA

Immunogen

Purified His-tagged TPIPb protein was used to produced this monoclonal antibody

Specificity

Human, Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

Ascites

Preservative

0.09% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2

Introduction

TPTE2 is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids.

Entrez Gene ID

93492

UniProt ID

Q6XPS3

Alternative Names

Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2; TPTE And PTEN Homologous Inositol Lipid Phosphatase; Lipid Phosphatase TPIP; TPIP; Transmembrane Phosphoinositide 3-Phosphatase And Tensin 2-Like Protein; Phosphatidylinositol 3, 4, 5-Trisphosphate 3-Phosphatase TPTE2; PTEN-Like Inositol Lipid Phosphatase; TPIP Lipid Phosphatase; EC 3.1.3.67

Function

Acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate.
Isoform 4
Shows no phosphoinositide phosphatase activity.

Biological Process

Biological Process cell motility Source:GO_Central1 Publication
Biological Process dephosphorylation Source:GO_Central1 Publication
Biological Process negative regulation of cell population proliferation Source:GO_Central1 Publication
Biological Process phosphatidylinositol 3-kinase signaling Source:GO_Central1 Publication
Biological Process phosphatidylinositol biosynthetic process Source:Reactome
Biological Process phosphatidylinositol dephosphorylation Source:GO_Central1 Publication
Biological Process protein dephosphorylation Source:GO_Central1 Publication
Biological Process regulation of protein kinase B signaling Source:GO_Central1 Publication

Cellular Location

Isoform 3
Endoplasmic reticulum membrane
Isoform 1
Endoplasmic reticulum membrane
Golgi apparatus membrane
Isoform 4
Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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