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Mouse Anti-TRAFD1 Recombinant Antibody (8E6E7) (CBMAB-T4041-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1). The antibody can be used for immunoassay techniques, such as ELISA, FC, ICC, IF, WB.
See all TRAFD1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
8E6E7
Antibody Isotype
IgG1
Application
ELISA, FC, ICC, IF, WB

Basic Information

Immunogen
The immunogen corresponding to a region within amino acids 401 and 582 of human TRAFD1 expressed in E. coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS
Preservative
0.05% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 401-582

Target

Full Name
TRAF-Type Zinc Finger Domain Containing 1
Introduction
The innate immune system confers host defense against viral and microbial infection. TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).
Entrez Gene ID
UniProt ID
Alternative Names
TRAF-Type Zinc Finger Domain Containing 1; FLN29; TRAF-Type Zinc Finger Domain-Containing Protein 1; FLN29 Gene Product; Protein FLN29
Function
Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).
Biological Process
Biological Process negative regulation of innate immune response Source:UniProtKB
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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