TRAFD1
The innate immune system confers host defense against viral and microbial infection. TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).
Full Name
TRAF-Type Zinc Finger Domain Containing 1
Function
Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).
Biological Process
Biological Process negative regulation of innate immune response Source:UniProtKB
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Anti-TRAFD1 antibodies
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Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2676
Application*: WB, F
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4130
Application*: IC, F
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4534
Application*: WB
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8E6E7
Application*: E, F, IC, IF, WB
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2368C3a
Application*: DB, WB
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4533
Application*: E, WB
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4532
Application*: E, F, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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