TRAFD1

The innate immune system confers host defense against viral and microbial infection. TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).
Full Name
TRAF-Type Zinc Finger Domain Containing 1
Function
Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).
Biological Process
Biological Process negative regulation of innate immune response Source:UniProtKB
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Anti-TRAFD1 antibodies

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Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2676
Application*: WB, F
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4130
Application*: IC, F
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4534
Application*: WB
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8E6E7
Application*: E, F, IC, IF, WB
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2368C3a
Application*: DB, WB
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4533
Application*: E, WB
Target: TRAFD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4532
Application*: E, F, WB
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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