TRAFD1

The innate immune system confers host defense against viral and microbial infection. TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).

Full Name

TRAF-Type Zinc Finger Domain Containing 1

Function

Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).

Biological Process

Biological Process negative regulation of innate immune response Source:UniProtKB

Anti-TRAFD1 antibodies

Mouse Anti-TRAFD1 Recombinant Antibody (2368C3a) (CBMAB-T4040-YJ)

Datasheet

SDS

Target: TRAFD1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2368C3a

Application*: DB, WB

Mouse Anti-TRAFD1 Recombinant Antibody (8E6E7) (CBMAB-T4041-YJ)

Datasheet

SDS

Target: TRAFD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 8E6E7

Application*: E, F, IC, IF, WB

Mouse Anti-TRAFD1 Recombinant Antibody (CBYJT-4532) (CBMAB-T4038-YJ)

Datasheet

SDS

Target: TRAFD1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-4532

Application*: E, F, WB

Mouse Anti-TRAFD1 Recombinant Antibody (CBYJT-4533) (CBMAB-T4039-YJ)

Datasheet

SDS

Target: TRAFD1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-4533

Application*: E, WB

Mouse Anti-TRAFD1 Recombinant Antibody (CBYJT-4534) (CBMAB-T4042-YJ)

Datasheet

SDS

Target: TRAFD1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-4534

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)