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Mouse Anti-TRAK2 Recombinant Antibody (S390-43) (CBMAB-1839-CN)

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Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
S390-43
Antibody Isotype
IgG2a
Application
WB, ICC, IF, IHC

Basic Information

Immunogen
Fusion protein of C-terminus of human TRAK2 (aa. 757-914).
Specificity
Human, Rat
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 50% Glycerol
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Trafficking Kinesin Protein 2
Introduction
This protein may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Entrez Gene ID
Human66008
Rat171086
UniProt ID
HumanO60296
RatQ8R2H7
Alternative Names
GRIF1; MILT2; OIP98; CALS-C; GRIF-1; ALS2CR3
Function
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Biological Process
Biological Process anterograde axonal transport of mitochondrion Source:GO_Central1 Publication
Biological Process anterograde dendritic transport of mitochondrion Source:Ensembl
Biological Process mitochondrion distribution Source:GO_Central1 Publication
Biological Process neurogenesis Source:GO_Central1 Publication
Biological Process protein targeting Source:GO_Central1 Publication
Biological Process vesicle transport along microtubule Source:GO_Central1 Publication
Cellular Location
Cytoplasm
Early endosome
Mitochondrion
Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity).
PTM
O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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