TRAK2

TRAK2 (Trafficking Kinesin Protein 2) is a Protein Coding gene. Diseases related to TRAK2 include Amyotrophic Lateral Sclerosis 2, Juvenile and Juvenile Amyotrophic Lateral Sclerosis. Among its related pathways are Metabolism and GABAergic synapse. Gene Ontology (GO) annotations related to TRAK2 include receptor binding and GABA receptor binding. An important paralog of TRAK2 is TRAK1.

Full Name

Trafficking Kinesin Protein 2

Function

May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.

Biological Process

Biological Process anterograde axonal transport of mitochondrion Source:GO_Central1 Publication
Biological Process anterograde dendritic transport of mitochondrion Source:Ensembl
Biological Process mitochondrion distribution Source:GO_Central1 Publication
Biological Process neurogenesis Source:GO_Central1 Publication
Biological Process protein targeting Source:GO_Central1 Publication
Biological Process vesicle transport along microtubule Source:GO_Central1 Publication

Cellular Location

Cytoplasm
Early endosome
Mitochondrion
Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity).

PTM

O-glycosylated.