Mouse Anti-TRAPPC9 Recombinant Antibody (CBYJT-4571) (CBMAB-T4084-YJ)

Name: Mouse Anti-TRAPPC9 Recombinant Antibody (CBYJT-4571)
SKU: CBMAB-T4084-YJ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBYJT-4571

Application

ELISA, IHC, WB

Specificity

Human, Mouse

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TRAPPC9 Gene(Protein Coding) Trafficking Protein Particle Complex 9

Introduction

TRAPPC9 is a protein that likely plays a role in NF-kappa-B signaling. Mutations in TRAPPC9 have been associated with autosomal-recessive cognitive disability.

Entrez Gene ID

Human	83696
Mouse	76510

UniProt ID

Human	Q96Q05
Mouse	Q3U0M1

Alternative Names

Trafficking Protein Particle Complex 9; NIK- And IKBKB-Binding Protein; Tularik Gene 1 Protein; TRAPP 120 KDa Subunit; NIBP; Trafficking Protein Particle Complex Subunit 9; NIK And IKK-Beta Binding Protein; IKK2 Binding Protein

Function

Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi.

Biological Process

Biological Process cerebral cortex development Source:GO_Central1 Publication
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport Source:ComplexPortal1 Publication
Biological Process neuron differentiation Source:Ensembl
Biological Process positive regulation of NF-kappaB transcription factor activity Source:Ensembl
Biological Process vesicle coating Source:ComplexPortal1 Publication
Biological Process vesicle tethering Source:ComplexPortal1 Publication

Cellular Location

Golgi apparatus, cis-Golgi network
Endoplasmic reticulum
Cytoplasm
Processes and cell bodies of neurons.

Involvement in disease

Intellectual developmental disorder, autosomal recessive 13 (MRT13):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected individuals.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-TRAPPC9 Recombinant Antibody (CF453) (CAT#: CBMAB-FT086LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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