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Mouse Anti-TRAPPC9 Recombinant Antibody (CF453) (CBMAB-FT086LY)

The product is antibody recognizes TRAPPC9. The antibody CF453 immunoassay techniques such as: ELISA, WB, IHC.
See all TRAPPC9 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CF453
Antibody Isotype
IgG1
Application
ELISA, WB, IHC

Basic Information

Immunogen
trafficking protein particle complex 9
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TRAPPC9 Gene(Protein Coding) Trafficking Protein Particle Complex 9
Introduction
This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive cognitive disability. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
Entrez Gene ID
83696
UniProt ID
Q96Q05
Alternative Names
IBP, IKBKBBP, KIAA1882, NIBP, NIK and IKBKB binding protein, T1, TRAPPC9, TRS120, Tularik gene 1 protein
Function
Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Biological Process
Biological Process cerebral cortex development Source:GO_Central1 Publication
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport Source:ComplexPortal1 Publication
Biological Process neuron differentiation Source:Ensembl
Biological Process positive regulation of NF-kappaB transcription factor activity Source:Ensembl
Biological Process vesicle coating Source:ComplexPortal1 Publication
Biological Process vesicle tethering Source:ComplexPortal1 Publication
Cellular Location
Golgi apparatus, cis-Golgi network
Endoplasmic reticulum
Cytoplasm
Processes and cell bodies of neurons.
Involvement in disease
Intellectual developmental disorder, autosomal recessive 13 (MRT13):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected individuals.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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